We explore the links between medical research in the Golden Age of Science and the modern practise of medicine today.

Standing in one of the largest neonatal units in the world at Hamad Hospital in Qatar, you would not immediately be able to draw a link between the pioneering medical research being conducted and the work of physicists from the ninth century.

In this episode of Science in the Golden Age, theoretical physicist Jim al-Khalili guides us through a journey of discovery where he highlights the links between medical research in the Golden Age of Science during the ninth and 14th centuries and the modern practise of medicine today.

At Hamad Hospital, a new treatment is being trialled for babies born with a neurological disorder called neonatal encephalopathy. Senior consultant Dr Samawal Lutfi explains how the double-blind placebo control method ensures the accuracy of the study.

This notion of a control group goes all the way back over 1,000 years to a Persian physician by the name of Al-Razi who built the first hospitals in Baghdad. He was an early proponent of applying a rigorous scientific approach to medicine and used a control group when testing methods to treat meningitis in the ninth century.

At Harefield Hospital in the UK, we meet the famous Egyptian Professor Magdi Yacoub, a pioneering transplant surgeon and one of the world’s leading heart specialists.

Professor Yacoub explains how the 13th-century scholar, Ibn al-Nafis, redefined the understanding of pulmonary circulation. He challenged the commonly accepted wisdom of the Greek scholar Galen, who had said that blood passes directly between the heart’s right and left ventricle through the septum, the dividing wall that separates them. Ibn al-Nafis put forward the idea that blood could not pass directly between the right and left chambers of the heart – and that the lungs had a role to play in this process.

Ibn al-Nafis’ description was not widely accepted at the time, and it wasn’t until his manuscript was rediscovered in the 20th century that his work was universally recognised.

From Al-Razi to Ibn al-Nafis, to the 10th-century philosopher and physician Ibn Sina, Khalili examines the most influential medics of the Golden Age. He shows us his personal copy of Ibn Sina’s Al-Qanun fi al-Tibb (The Canon of Medicine), a comprehensive text which was the pinnacle of medical knowledge at that time. It was widely copied and translated, becoming a standard medical reference across the world for centuries.

Khalili ends his journey at the Weill Cornell Medical College in Qatar, learning how the institute is using the latest equipment to map the human genome. The genome is the complex genetic code contained in every one of our cells and sequencing it can reveal possible hereditary diseases.

Focusing on genetic and hereditary diseases specifically affecting the Qatari population, scientists from around the world have come together to work on this ambitious project that somewhat parallels Baghdad’s Bayt al-Hikma (The House of Wisdom), the renowned centre of learning that played an integral role in the Islamic world’s scientific advancement.